Lung cancer remains the leading cause of cancer death in South Carolina, affecting nearly 4,000 residents each year, according to SC Department of Public Health. Non-small cell lung cancer makes up about 84% of all lung cancers and is a life-threatening late-stage diagnosis. Advanced conditions place heavy physical and emotional burdens on patients and their families.
At the university’s Cancer Survivorship Research Center, nurse scientists are leading innovative studies to help people living with and beyond lung cancer better manage symptoms, maintain treatment, and enhance their quality of life.
Helping patients manage side effects
Karen Wickersham is leading a first-of-its-kind, phone-based self-management study designed to help patients with advanced lung cancer manage the difficult side effects of targeted medications.
The 10-week program focuses on strengthening patients’ confidence, coping skills, and support systems through weekly one-on-one phone sessions with a trained interventionist. Participants learn practical strategies for managing side effects, reducing stress, and staying on track with their prescribed therapies.
“Patients want to take their medicine, but the side effects can be overwhelming,” Wickersham says. “Our goal is to help them manage symptoms and stay on their life-improving therapy.”
Supporting survivor resilience
Meanwhile, Amanda Dyer and Pamela Wright are leading Breathe Easier Plus (BE+), a 12-week, home-based recovery program that combines mindfulness, guided walking, and live virtual strength training.
“Breathe Easier+ reflects our commitment to scalable, survivor and partner-inclusive care,” says Dyer.
Survivors and their support partners receive personalized coaching, digital reminders, and weekly motivation. Early results show stronger bodies, better sleep and reduced stress.
“Lung cancer survivors often feel left behind once treatment ends,” Wright says. “BE+ gives them the tools and confidence to thrive again.”
Leading the way in lung cancer research
Together, these studies highlight USC Nursing’s growing leadership in cancer survivorship research, addressing both the physical and emotional dimensions of recovery. By empowering patients to take control of their treatment and rebuild strength at home, these researchers are redefining what it means to live well after an advanced lung cancer diagnosis.
Gov. Henry McMaster will proclaim November as Lung Cancer Awareness Month, recognizing the Palmetto State’s ongoing commitment to improving lung cancer care and survivorship.